A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay.
Identifieur interne : 002283 ( Main/Exploration ); précédent : 002282; suivant : 002284A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay.
Auteurs : Jing Lin [États-Unis] ; Francesca M. Bruni ; Zhiyan Fu ; Jennifer Maloney ; Ludmilla Bardina ; Attilio L. Boner ; Gustavo Gimenez ; Hugh A. SampsonSource :
- The Journal of allergy and clinical immunology [ 1097-6825 ] ; 2012.
Descripteurs français
- KwdFr :
- Adolescent, Albumines 2S de plante (immunologie), Albumines 2S de plante (métabolisme), Analyse par réseau de protéines, Antigènes végétaux (immunologie), Antigènes végétaux (métabolisme), Biologie informatique (), Enfant, Enfant d'âge préscolaire, Femelle, Glycoprotéines (immunologie), Glycoprotéines (métabolisme), Humains, Hypersensibilité à l'arachide (diagnostic), Hypersensibilité à l'arachide (immunologie), Immunisation, Immunoglobuline E (métabolisme), Immunoglobuline G (métabolisme), Modèles biologiques, Mâle, Protéines membranaires, Protéines végétales (immunologie), Protéines végétales (métabolisme), Valeur prédictive des tests, Épitopes (immunologie), Épitopes (métabolisme).
- MESH :
- diagnostic : Hypersensibilité à l'arachide.
- immunologie : Albumines 2S de plante, Antigènes végétaux, Glycoprotéines, Hypersensibilité à l'arachide, Protéines végétales, Épitopes.
- métabolisme : Albumines 2S de plante, Antigènes végétaux, Glycoprotéines, Immunoglobuline E, Immunoglobuline G, Protéines végétales, Épitopes.
- Adolescent, Analyse par réseau de protéines, Biologie informatique, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Immunisation, Modèles biologiques, Mâle, Protéines membranaires, Valeur prédictive des tests.
English descriptors
- KwdEn :
- 2S Albumins, Plant (immunology), 2S Albumins, Plant (metabolism), Adolescent, Antigens, Plant (immunology), Antigens, Plant (metabolism), Child, Child, Preschool, Computational Biology (methods), Epitopes (immunology), Epitopes (metabolism), Female, Glycoproteins (immunology), Glycoproteins (metabolism), Humans, Immunization, Immunoglobulin E (metabolism), Immunoglobulin G (metabolism), Male, Membrane Proteins, Models, Biological, Peanut Hypersensitivity (diagnosis), Peanut Hypersensitivity (immunology), Plant Proteins (immunology), Plant Proteins (metabolism), Predictive Value of Tests, Protein Array Analysis.
- MESH :
- chemical , immunology : 2S Albumins, Plant, Antigens, Plant, Epitopes, Glycoproteins, Plant Proteins.
- chemical , metabolism : 2S Albumins, Plant, Antigens, Plant, Epitopes, Glycoproteins, Immunoglobulin E, Immunoglobulin G, Plant Proteins.
- diagnosis : Peanut Hypersensitivity.
- immunology : Peanut Hypersensitivity.
- methods : Computational Biology.
- Adolescent, Child, Child, Preschool, Female, Humans, Immunization, Male, Membrane Proteins, Models, Biological, Predictive Value of Tests, Protein Array Analysis.
Abstract
Peanut allergy is relatively common, typically permanent, and often severe. Double-blind, placebo-controlled food challenge is considered the gold standard for the diagnosis of food allergy-related disorders. However, the complexity and potential of double-blind, placebo-controlled food challenge to cause life-threatening allergic reactions affects its clinical application. A laboratory test that could accurately diagnose symptomatic peanut allergy would greatly facilitate clinical practice.
DOI: 10.1016/j.jaci.2012.02.012
PubMed: 22444503
Affiliations:
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Le document en format XML
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Double-blind, placebo-controlled food challenge is considered the gold standard for the diagnosis of food allergy-related disorders. However, the complexity and potential of double-blind, placebo-controlled food challenge to cause life-threatening allergic reactions affects its clinical application. A laboratory test that could accurately diagnose symptomatic peanut allergy would greatly facilitate clinical practice.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>État de New York</li></region></list><tree><noCountry><name sortKey="Bardina, Ludmilla" sort="Bardina, Ludmilla" uniqKey="Bardina L" first="Ludmilla" last="Bardina">Ludmilla Bardina</name><name sortKey="Boner, Attilio L" sort="Boner, Attilio L" uniqKey="Boner A" first="Attilio L" last="Boner">Attilio L. Boner</name><name sortKey="Bruni, Francesca M" sort="Bruni, Francesca M" uniqKey="Bruni F" first="Francesca M" last="Bruni">Francesca M. Bruni</name><name sortKey="Fu, Zhiyan" sort="Fu, Zhiyan" uniqKey="Fu Z" first="Zhiyan" last="Fu">Zhiyan Fu</name><name sortKey="Gimenez, Gustavo" sort="Gimenez, Gustavo" uniqKey="Gimenez G" first="Gustavo" last="Gimenez">Gustavo Gimenez</name><name sortKey="Maloney, Jennifer" sort="Maloney, Jennifer" uniqKey="Maloney J" first="Jennifer" last="Maloney">Jennifer Maloney</name><name sortKey="Sampson, Hugh A" sort="Sampson, Hugh A" uniqKey="Sampson H" first="Hugh A" last="Sampson">Hugh A. Sampson</name></noCountry><country name="États-Unis"><region name="État de New York"><name sortKey="Lin, Jing" sort="Lin, Jing" uniqKey="Lin J" first="Jing" last="Lin">Jing Lin</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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